Problems with conceiving and bearing a child are not uncommon today. During this period, a huge mechanism should be established in the body of a woman. And even a small glitch in it can lead to serious consequences. A very important role in the work of the body is played by the balance of hormones. His deviation in one direction or another will seriously affect not only pregnancy, but also the health of the mother. The disadvantage of one of them can be made up for with Progesterone.
This drug is obtained synthetically, and in its molecular structure it belongs to steroids. It is necessary for the proper functioning of the menstrual cycle, reduce uterine excitability, stimulate the activity of the mammary gland, and also to activate the transition of the uterine mucosa from the proliferation phase to the secretory phase.
Progesterone instructions for use
The norm of progesterone in women
The level of this hormone varies depending on the phase of the menstrual cycle and the trimester of pregnancy. The minimum level of progesterone is observed in the follicular phase and is equal to 0.32 - 2.25 nmol / L. The largest level of this hormone is observed in the third trimester of pregnancy and is 88.7 - 771.5 nmol / L.
With a hormone deficiency, women can be diagnosed with infertility. If the level of progesterone is high, but the woman is not pregnant, then this is a signal about the presence of the disease. Such diseases include the formation of a malignant tumor, ovarian disease and other problems.
How does the drug Progesterone
Use this hormonal drug with a lack of corpus luteum. Such a deficiency can lead to miscarriage, premature birth and infertility. In addition, "Progesterone" is prescribed for amenorrhea, uterine bleeding, dysmenorrhea and other problems.
Often, under the influence of various factors, the action of internal organs is disturbed. The most common cause of malfunctioning of the internal organs of the body in women is hormonal failure. And most often it occurs with a deficiency of the hormone progesterone.
This drug is available in the form of a solution for injection of 1% or 2.5%.
Indications for use
"Progesterone" is prescribed for corpus luteum insufficiency, threatening preterm birth, the threat of miscarriage, premature pregnancy, uterine bleeding, etc.
Injections of this drug are prescribed if progesterone deficiency is detected on days 22-23 from the start of the monthly cycle. Also, it can be prescribed if a woman already had two miscarriages at the time of going to the doctor.
Progesterone in Pregnancy
During pregnancy, this drug is prescribed quite often. The attending physician, based on the patient’s medical parameters, may prescribe progesterone injections in the absence of this hormone in the body. The use of the drug after 37 weeks of pregnancy is contraindicated.
This tool can not be used for tumors in the chest and reproductive organs. In addition, contraindications to the use of "Progesterone" are abnormalities in the liver, thrombosis, hepatitis and spotting.
Interaction with other drugs
The drug in question in this article weakens the effects of anabolic steroids, pituitary hormones and drugs that stimulate the reduction of myometrium. Progesterone may enhance the effects of antihypertensive drugs, diuretics, immunosuppressants and systemic coagulants.
The drug is allowed to be used only as directed by a doctor. Injections of this agent are administered intramuscularly in 1 ml of a 1.0% or 2.5% solution. The course of treatment is 6-8 days.
- With dysmenorrhea, the dosage should be 0.003-0.005 g daily. 4-6 days course
- With amenorrhea, the dosage is 0.005-0.010 g daily. Course 6 - 8 days
- With a deficiency of the corpus luteum, the dosage is 12.5 mg daily (from the day of ovulation). 14 days course
- With uterine bleeding, a dosage of 0.005 g daily. Course 5 - 8 days
- If there is a risk of miscarriage, the dosage is 0.005-0.010-0.025 g daily. Course up to 4 months of pregnancy
With an overdose of this hormonal agent, retinal vein thrombosis can develop. As a result, vision can be severely impaired. Also, an excess of the maximum dose of "Progesterone" causes apathy and drowsiness. May lead to edema and allergic reactions.
The drug is sold in ampoules with an oily liquid of a yellowish or greenish tint. One ampoule contains 0.01 g or 0.025 g of progesterone. As well as excipients: medical benzyl benzoate and ethyl oleate.
Progesterone or Duphaston?
Active substance Dufaston is a synthetic analogue of progesterone - dydrogesterone. The drug is available in the form of tablets and is used for progesterone deficiency. It is believed that this tool has no side effects. The release form of Duphaston makes it easier to use it to increase progesterone in the body than by injection.
Experts believe that before pregnancy it is more advisable to drink "Duphaston." Whereas during the first trimester of pregnancy it is better to use Progesterone.
Klimonorm - a remedy prescribed for menopausal disorders. Available in the form of dragees. The active substances are estradiol valerate and levonorgestrel.
- Dosage: 1 tablet once a day. Course: prescribed by a doctor
"Utrozhestan" - a drug for the treatment of progesterone deficiency. Available in capsule form. The active substance is progesterone natural micronized.
- Dosage: 200 - 400 mg daily (2 doses). Course: prescribed by a doctor
Menorma - a plant-based drug used to normalize the flow of menstruation. Available in tablet form. Active ingredients: herbal bag herb extract, viburnum bark extract and rutin.
- Dosage: 1 tablet 2 times a day. Course: as prescribed by the doctor
Divina - a means to restore estrogen levels and prevention of postmenopausal osteoporosis. Available in tablet form. Active ingredients: Estradiol and Medroxyprogesterone.
- Dosage: 1 white tablet per day for 70 days of the cycle, from 71 to 84 days - blue tablets, from 85 to 91 days - yellow tablets. Course: as prescribed by the doctor
Olga I took this medicine to restore the cycle. I suffered from this problem until they advised a good gynecologist-endocrinologist. She looked at my tests and prescribed progesterone. The cycle returned to normal. But, I'm afraid when I stop injecting this hormone, again everything will go astray.
Kira. I drink Dufaston. At the first pregnancy, progesterone was prescribed. So my cones did not resolve for a very long time from injections. It’s better to drink pills. Although they say that they are not fully absorbed. But everything seems to be fine.